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DDF structures illustrated by Emily J. Wu and Ankita T. Kandalkar from the Hao Wu lab
Last updated on December 23, 2024.
DD: death domain; DED: death effector domain; CARD: caspase recruitment domain; PYD: pyrin domain. The work was supported by grants from the US National Institutes of Health.
Protein or complex | PDB ID | Image | Residues | 3D structure | Source Organism | Resolution (Å)-2 | Unitprot | Method | Publication |
|---|---|---|---|---|---|---|---|---|---|
p100 DD | 2D96 |  | 1-109 | 2D96-3D | Homo sapiens | - | Q00653 | NMR | 2006 |
p84 DD | 1WXP |  | 1-110 | 1WXP-3D | Homo sapiens | - | Q96FV9 | NMR | 2005 |
Pelle DD | 1YGO |  | 1-110 | 1YGO-3D | Drosophila melanogaster | - | Q05652 | NMR | 2005-Moncrieffe |
CED-4 CARD: CED-3 CARD | 8JO0 |  | 1-110 | 8JO0-3D | Caenorhabditis elegans | 4.0 | P30429 | EM | 2023-Li |
NALP10 PYD | 2DO9 |  | 1-115 | 2DO9-3D | Mus musculus | - | Q8CCN1 | NMR | 2006 |
IRAK-M DD, R56D, Y61E | 5UKE |  | 1-124 | 5UKE-3D | Homo sapiens | - | Q9Y616 | NMR | 2018-Nechama |
IRAK4 DD | 1WH4 |  | 1-127 | 1WH4-3D | Mus musculus | - | Q8R4K2 | NMR | 2004 |
PEA-15 DED | 1N3K |  | 1-130 | 1N3K-3D | Cricetulus griseus | - | Q9Z297 | NMR | 2002-Hill |
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